虎扑电竞 虎扑电竞

A research group has revealed a cobalt-chromium-based biomaterial that mimics the flexibility of human bones and possesses excellent wear resistance. The new biomaterial could be used for implants such as hip or knee joint replacements and bone plates, alleviating problems associated with conventional implant materials.

Details of their research were published in the journal Advanced Materials on May 9, 2022.

With the elderly population increasing across the globe, the need for improved biomaterials that can replace or support damaged bones has risen. For this purpose, metals are widely used because of their strength and ductility. However, as a consequence of their strength, their flexibility diminishes.

To date, most metallic biomaterials are stiffer than human bones, and using them as implants leads to bone atrophy - a condition where bone density is reduced because of a breakdown in bone substance and structure. Meanwhile, biomaterials with elevated flexibility lose their wear resistance.

Although superelastic materials made from nickel-titanium (Ni-Ti) alloys, which are commonly used in stents and orthodontic wires, maintain high flexibility and the ability to recover from strain, Ni is an allergic element. Ni-free alloys have not replicated the superelasticity of Ni-Ti alloys, rendering them impractical.

The research group, which comprised researchers from Tohoku University's Graduate School of Engineering and Institute for Materials 虎扑电竞 (IMR), the J-PARC Center, the Japan Atomic Energy 虎扑电竞ncy, and the Czech Academy of Sciences, focused on lessening the Young's modulus gap between metal implants and human bones. When a material is flexible, it has a low Young's modulus. When it is stiff, it has a high Young's modulus.

"Since the Young's modulus hinges on crystal orientation, we grew single crystals with a specific crystal orientation," said Xiao Xu, corresponding author and assistant professor at Tohoku University's Graduate School of Engineering.

Using a cyclical heat treatment technique, Xu and his colleagues successfully prepared large single crystals sized several centimeters. The developed Co-Cr-Al-Si (CCAS) alloy demonstrated a 17% strain recovery rate - twice that of commercial Ti-Ni shape memory alloys. Moreover, the CCAS's Young's modulus was extremely low, resembling the flexibility of human bones.

"We knew that chromium possesses strong corrosive resistance, but the superelasticity, flexibility, and significant wear resistance of the cobalt-chromium-based material surprised us," added Xu.

Moving forward, the research group hopes to explore why their CCAS achieved the superior properties it did. Doing so could lead to developing next-generation materials with even better properties.

Publication Details:

Title: Flexible and Tough Superelastic Co-Cr Alloys for Biomedical Applications
Authors: Takumi Odaira, Sheng Xu, Kenji Hirata, Xiao Xu, Toshihiro Omori, Kosuke Ueki, Kyosuke Ueda, Takayuki Narushima, Makoto Nagasako, Stefanus Harjo, Takuro Kawasaki, Lucie Bodnárová, Petr Sedlák, Hanu? Seiner, Ryosuke Kainuma
Journal: Advanced Materials
DOI: 10.1002/adma.202202305

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